A gut microbial peptide and molecular mimicry in the pathogenesis of type 1 diabetes

Type 1 diabetes (T1D) is an autoimmune disease characterized by the destruction of pancreatic β-cells. One of the earliest aspects of this process is the development of autoantibodies and T cells directed at an epitope in the B-chain of insulin (insB:9–23). Analysis of microbial protein sequences wi...

Descripción completa

Detalles Bibliográficos
Autores principales: Girdhar, Khyati, Huang, Qian, Chow, I-Ting, Vatanen, Tommi, Brady, Claudia, Raisingani, Amol, Autissier, Patrick, Atkinson, Mark A., Kwok, William W., Kahn, C. Ronald, Altindis, Emrah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351354/
https://www.ncbi.nlm.nih.gov/pubmed/35878027
http://dx.doi.org/10.1073/pnas.2120028119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351354/
https://www.ncbi.nlm.nih.gov/pubmed/35878027
http://dx.doi.org/10.1073/pnas.2120028119

Ejemplares similares