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Calorie Restriction Rescues Mitochondrial Dysfunction in Adck2-Deficient Skeletal Muscle

ADCK2 haploinsufficiency-mediated mitochondrial coenzyme Q deficiency in skeletal muscle causes mitochondrial myopathy associated with defects in beta-oxidation of fatty acids, aged-matched metabolic reprogramming, and defective physical performance. Calorie restriction has proven to increase lifesp...

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Detalles Bibliográficos
Autores principales: Hernández-Camacho, Juan Diego, Fernández-Ayala, Daniel J. M., Vicente-García, Cristina, Navas-Enamorado, Ignacio, López-Lluch, Guillermo, Oliva, Clara, Artuch, Rafael, Garcia-Villoria, Judith, Ribes, Antonia, de Cabo, Rafael, Carvajal, Jaime J., Navas, Plácido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351392/
https://www.ncbi.nlm.nih.gov/pubmed/35936917
http://dx.doi.org/10.3389/fphys.2022.898792