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Transcription factor EB coordinates environmental cues to regulate T regulatory cells’ mitochondrial fitness and function

T regulatory (Treg) cells are essential for self-tolerance whereas they are detrimental for dampening the host anti-tumor immunity. How Treg cells adapt to environmental signals to orchestrate their homeostasis and functions remains poorly understood. Here, we identified that transcription factor EB...

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Detalles Bibliográficos
Autores principales: Xia, Minghui, Zhang, Cai, Chen, Yufei, Zhao, Xiujuan, Zhang, Si, Liu, Yang, Cai, You, Wei, Zhengping, Du, Qiuyang, Yu, Wenting, Zhou, Chun, Xiao, Hongjun, Wang, Guihua, Cheng, Xiang, Mei, Heng, Laurence, Arian, Wang, Jing, Hu, Yu, Li, Huabin, Yang, Xiang-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351480/
https://www.ncbi.nlm.nih.gov/pubmed/35895684
http://dx.doi.org/10.1073/pnas.2205469119