Molecular determinants of pH sensing in the proton-activated chloride channel

In response to acidic pH, the widely expressed proton-activated chloride (PAC) channel opens and conducts anions across cellular membranes. By doing so, PAC plays an important role in both cellular physiology (endosome acidification) and diseases associated with tissue acidosis (acid-induced cell de...

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Detalles Bibliográficos
Autores principales: Osei-Owusu, James, Kots, Ekaterina, Ruan, Zheng, Mihaljević, Ljubica, Chen, Kevin Hong, Tamhaney, Ami, Ye, Xinyu, Lü, Wei, Weinstein, Harel, Qiu, Zhaozhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351481/
https://www.ncbi.nlm.nih.gov/pubmed/35878032
http://dx.doi.org/10.1073/pnas.2200727119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351481/
https://www.ncbi.nlm.nih.gov/pubmed/35878032
http://dx.doi.org/10.1073/pnas.2200727119

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