Physical and in silico immunopeptidomic profiling of a cancer antigen prostatic acid phosphatase reveals targets enabling TCR isolation

Tissue-specific antigens can serve as targets for adoptive T cell transfer-based cancer immunotherapy. Recognition of tumor by T cells is mediated by interaction between peptide–major histocompatibility complexes (pMHCs) and T cell receptors (TCRs). Revealing the identity of peptides bound to MHC is...

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Detalles Bibliográficos
Autores principales: Mao, Zhiyuan, Nesterenko, Pavlo A., McLaughlin, Jami, Deng, Weixian, Burton Sojo, Giselle, Cheng, Donghui, Noguchi, Miyako, Chour, William, DeLucia, Diana C., Finton, Kathryn A., Qin, Yu, Obusan, Matthew B., Tran, Wendy, Wang, Liang, Bangayan, Nathanael J., Ta, Lisa, Chen, Chia-Chun, Seet, Christopher S., Crooks, Gay M., Phillips, John W., Heath, James R., Strong, Roland K., Lee, John K., Wohlschlegel, James A., Witte, Owen N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351518/
https://www.ncbi.nlm.nih.gov/pubmed/35878026
http://dx.doi.org/10.1073/pnas.2203410119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351518/
https://www.ncbi.nlm.nih.gov/pubmed/35878026
http://dx.doi.org/10.1073/pnas.2203410119

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