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A missense mutation in Kcnc3 causes hippocampal learning deficits in mice
Although a wide variety of genetic tools has been developed to study learning and memory, the molecular basis of memory encoding remains incompletely understood. Here, we undertook an unbiased approach to identify novel genes critical for memory encoding. From a large-scale, in vivo mutagenesis scre...
Autores principales: | Xu, Pin, Shimomura, Kazuhiro, Lee, Changhoon, Gao, Xiaofei, Simpson, Eleanor H., Huang, Guocun, Joseph, Chryshanthi M., Kumar, Vivek, Ge, Woo-Ping, Pawlowski, Karen S., Frye, Mitchell D., Kourrich, Saïd, Kandel, Eric R., Takahashi, Joseph S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351536/ https://www.ncbi.nlm.nih.gov/pubmed/35881790 http://dx.doi.org/10.1073/pnas.2204901119 |
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