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Photoreceptor Cells Constitutively Express IL-35 and Promote Ocular Immune Privilege

Interleukin-27 is constitutively secreted by microglia in the retina or brain, and upregulation of IL-27 during neuroinflammation suppresses encephalomyelitis and autoimmune uveitis. However, while IL-35 is structurally and functionally similar to IL-27, the intrinsic roles of IL-35 in CNS tissues a...

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Detalles Bibliográficos
Autores principales: Yu, Cheng-Rong, Yadav, Manoj Kumar, Kang, Minkyung, Jittayasothorn, Yingyos, Dong, Lijin, Egwuagu, Charles E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351654/
https://www.ncbi.nlm.nih.gov/pubmed/35897732
http://dx.doi.org/10.3390/ijms23158156