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Lactic acidosis, a potential toxicity from drug–drug interaction related to concomitant ribociclib and metformin in preexisting renal insufficiency: A case report

BACKGROUND: Ribociclib, one of the cyclin‐dependent kinases (CDK) 4 and 6 inhibitors, in combination with endocrine therapies has been approved in the treatment of hormonal receptor positive, HER‐2 negative metastatic breast cancer worldwide. Long‐term usage of ribociclib with concomitant drugs, pot...

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Detalles Bibliográficos
Autores principales: Lagampan, Chalita, Poovorawan, Nattaya, Parinyanitikul, Napa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351659/
https://www.ncbi.nlm.nih.gov/pubmed/34739192
http://dx.doi.org/10.1002/cnr2.1575