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CD44 Glycosylation as a Therapeutic Target in Oncology

The interaction of non-kinase transmembrane glycoprotein CD44 with ligands including hyaluronic acid (HA) is closely related to the occurrence and development of tumors. Changes in CD44 glycosylation can regulate its binding to HA, Siglec-15, fibronectin, TM4SF5, PRG4, FGF2, collagen and podoplanin...

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Detalles Bibliográficos
Autores principales: Liao, Chengcheng, Wang, Qian, An, Jiaxing, Chen, Jie, Li, Xiaolan, Long, Qian, Xiao, Linlin, Guan, Xiaoyan, Liu, Jianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351704/
https://www.ncbi.nlm.nih.gov/pubmed/35936713
http://dx.doi.org/10.3389/fonc.2022.883831