Cargando…

CD44 Glycosylation as a Therapeutic Target in Oncology

The interaction of non-kinase transmembrane glycoprotein CD44 with ligands including hyaluronic acid (HA) is closely related to the occurrence and development of tumors. Changes in CD44 glycosylation can regulate its binding to HA, Siglec-15, fibronectin, TM4SF5, PRG4, FGF2, collagen and podoplanin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liao, Chengcheng, Wang, Qian, An, Jiaxing, Chen, Jie, Li, Xiaolan, Long, Qian, Xiao, Linlin, Guan, Xiaoyan, Liu, Jianguo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351704/ https://www.ncbi.nlm.nih.gov/pubmed/35936713 http://dx.doi.org/10.3389/fonc.2022.883831

Ejemplares similares

SPINKs in Tumors: Potential Therapeutic Targets
por: Liao, Chengcheng, et al.
Publicado: (2022)

B7 family protein glycosylation: Promising novel targets in tumor treatment
por: Xiao, Linlin, et al.
Publicado: (2022)

Changes in Protein Glycosylation in Head and Neck Squamous Cell Carcinoma
por: Liao, Chengcheng, et al.
Publicado: (2021)

Glycosylation of CD44 is implicated in CD44-mediated cell adhesion to hyaluronan
Publicado: (1996)

The Therapeutic Effects of DDP/CD44-shRNA Nanoliposomes in AMF on Ovarian Cancer
por: Guo, Ting, et al.
Publicado: (2022)

Targeting Ovarian Cancer Cells Overexpressing CD44 with Immunoliposomes Encapsulating Glycosylated Paclitaxel
por: Khayrani, Apriliana Cahya, et al.
Publicado: (2019)

Glycosylation of CD44 negatively regulates its recognition of hyaluronan
Publicado: (1995)

Partial EMT in Squamous Cell Carcinoma: A Snapshot
por: Liao, Chengcheng, et al.
Publicado: (2021)

Pyruvate dehydrogenase kinase as a novel therapeutic target in oncology
por: Sutendra, Gopinath, et al.
Publicado: (2013)

A Systematic Review to Clarify the Prognostic Values of CD44 and CD44(+)CD24(-) Phenotype in Triple-Negative Breast Cancer Patients: Lessons Learned and The Road Ahead
por: Abdoli Shadbad, Mahdi, et al.
Publicado: (2021)

CD44 In Sarcomas: A Comprehensive Review and Future Perspectives
por: Fernández-Tabanera, Enrique, et al.
Publicado: (2022)

CD44 expressed by myeloid cells promotes glioma invasion
por: Ivanova, Ekaterina L., et al.
Publicado: (2022)

Glycosylated Nanoparticles for Cancer-Targeted Drug Delivery
por: Torres-Pérez, Sergio Andrés, et al.
Publicado: (2020)

Glycosylation of Glycolipids in Cancer: Basis for Development of Novel Therapeutic Approaches
por: Daniotti, Jose L., et al.
Publicado: (2013)

Regulation of CD44 binding to hyaluronan by glycosylation of variably spliced exons
Publicado: (1995)

FUT8 and Protein Core Fucosylation in Tumours: From Diagnosis to Treatment
por: Liao, Chengcheng, et al.
Publicado: (2021)

CD44: A metastasis driver and therapeutic target
por: Sottnik, Joseph L., et al.
Publicado: (2016)

CD44 as a tumor biomarker and therapeutic target
por: Xu, Hanxiao, et al.
Publicado: (2020)

Abnormal Glycosylation of Cancer Stem Cells and Targeting Strategies
por: Khan, Thahomina, et al.
Publicado: (2021)

Therapeutic Targeting of the Macrophage Immune Checkpoint CD47 in Myeloid Malignancies
por: Chao, Mark P., et al.
Publicado: (2020)

Understanding Hyaluronan Receptor (CD44) Interaction, HA-CD44 Activated Potential Targets in Cancer Therapeutics
por: Chaudhry, Gul-e-Saba, et al.
Publicado: (2021)

The Glycosylation of Immune Checkpoints and Their Applications in Oncology
por: Zheng, Linlin, et al.
Publicado: (2022)

The Prognostic and Clinical Value of CD44 in Colorectal Cancer: A Meta-Analysis
por: Wang, Zhenpeng, et al.
Publicado: (2019)

Effect of chewing gum on orthodontic pain in patients receiving fixed orthodontic treatment: a systematic review and meta-analysis
por: Guo, Qiushuang, et al.
Publicado: (2023)

SIRT1, a novel transcriptional downstream target of CD44, linking its deacetylase activity to tumor cell invasion/metastasis
por: Ahmad, Salma M. S., et al.
Publicado: (2022)

PCF11, a Novel CD44-Downstream Transcriptional Target, Linking Its 3’-End Polyadenylation Function to Tumor Cell Metastasis
por: Al-Mansoob, Maryam, et al.
Publicado: (2022)

CD44 expression in curettage and postoperative specimens of endometrial cancer
por: Wojciechowski, Michał, et al.
Publicado: (2014)

Editorial: Developmental therapeutics in pediatric neuro-oncology
por: Makimoto, Atsushi, et al.
Publicado: (2023)

Glycosylated Notch and Cancer
por: Pakkiriswami, Shanmugasundaram, et al.
Publicado: (2016)

Key Roles of Hyaluronan and Its CD44 Receptor in the Stemness and Survival of Cancer Stem Cells
por: Chanmee, Theerawut, et al.
Publicado: (2015)

Overexpression of Specific CD44 Isoforms Is Associated with Aggressive Cell Features in Acquired Endocrine Resistance
por: Bellerby, Rebecca, et al.
Publicado: (2016)

Enrichment of CD44 in Exosomes From Breast Cancer Cells Treated With Doxorubicin Promotes Chemoresistance
por: Wang, Xiaohong, et al.
Publicado: (2020)

CD44 in Ovarian Cancer Progression and Therapy Resistance—A Critical Role for STAT3
por: Martincuks, Antons, et al.
Publicado: (2020)

SFPQ Promotes Lung Cancer Malignancy via Regulation of CD44 v6 Expression
por: Yang, Libang, et al.
Publicado: (2022)

Radiation-Induced Reprogramming of Pre-Senescent Mammary Epithelial Cells Enriches Putative CD44(+)/CD24(−/low) Stem Cell Phenotype
por: Gao, Xuefeng, et al.
Publicado: (2016)

Glycosylated Cathepsin V Serves as a Prognostic Marker in Lung Cancer
por: Yang, Lewei, et al.
Publicado: (2022)

Biosynthetic Machinery Involved in Aberrant Glycosylation: Promising Targets for Developing of Drugs Against Cancer
por: Vasconcelos-dos-Santos, Andréia, et al.
Publicado: (2015)

CD44 Expression Profile Varies According to Maturational Subtypes and Molecular Profiles of Pediatric T-Cell Lymphoblastic Leukemia
por: Marques, Luísa Vieira Codeço, et al.
Publicado: (2018)

CD47 as a promising therapeutic target in oncology
por: Zhao, Hai, et al.
Publicado: (2022)

Metabolic Rewiring in Radiation Oncology Toward Improving the Therapeutic Ratio
por: van Gisbergen, Marike W., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_q8ju64k7iddj2eo4uql34op4sk