The inositol 5-phosphatase INPP5B regulates B cell receptor clustering and signaling

Upon antigen binding, the B cell receptor (BCR) undergoes clustering to form a signalosome that propagates downstream signaling required for normal B cell development and physiology. BCR clustering is dependent on remodeling of the cortical actin network, but the mechanisms that regulate actin remod...

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Detalles Bibliográficos
Autores principales: Droubi, Alaa, Wallis, Connor, Anderson, Karen E., Rahman, Saifur, de Sa, Aloka, Rahman, Taufiq, Stephens, Len R., Hawkins, Philip T., Lowe, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351708/
https://www.ncbi.nlm.nih.gov/pubmed/35878408
http://dx.doi.org/10.1083/jcb.202112018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351708/
https://www.ncbi.nlm.nih.gov/pubmed/35878408
http://dx.doi.org/10.1083/jcb.202112018

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