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Beverage-induced enhanced bioavailability of carbamazepine and its consequent effect on antiepileptic activity and toxicity

The present study was undertaken to investigate the food–drug interaction of carbamazepine (CBZ). Common fruit juices [grapefruit juice (GFJ), lime juice (LJ)], known to inhibit the enzyme cytochrome P450 3A4 (CYP3A4), and some widely consumed beverages [milk (M), black tea (BT)] were involved in th...

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Detalles Bibliográficos
Autores principales: Karmakar, Sanmoy, Biswas, Sreerupa, Bera, Rammohan, Mondal, Samiran, Kundu, Amit, Ali, Md Asif, Sen, Tuhinadri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taiwan Food and Drug Administration 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351769/
https://www.ncbi.nlm.nih.gov/pubmed/28911389
http://dx.doi.org/10.1016/j.jfda.2014.07.012