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Beverage-induced enhanced bioavailability of carbamazepine and its consequent effect on antiepileptic activity and toxicity
The present study was undertaken to investigate the food–drug interaction of carbamazepine (CBZ). Common fruit juices [grapefruit juice (GFJ), lime juice (LJ)], known to inhibit the enzyme cytochrome P450 3A4 (CYP3A4), and some widely consumed beverages [milk (M), black tea (BT)] were involved in th...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taiwan Food and Drug Administration
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351769/ https://www.ncbi.nlm.nih.gov/pubmed/28911389 http://dx.doi.org/10.1016/j.jfda.2014.07.012 |