Amino substituted nitrogen heterocycle ureas as kinase insert domain containing receptor (KDR) inhibitors: Performance of structure–activity relationship approaches

A quantitative structure–activity relationship (QSAR) study was performed on a set of amino-substituted nitrogen heterocyclic urea derivatives. Two novel approaches were applied: (1) the simplified molecular input-line entry systems (SMILES) based optimal descriptors approach; and (2) the fragment-b...

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Detalles Bibliográficos
Autores principales: Yilmaz, Hayriye, Sizochenko, Natalia, Rasulev, Bakhtiyor, Toropov, Andrey, Guzel, Yahya, Kuz’min, Viktor, Leszczynska, Danuta, Leszczynski, Jerzy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taiwan Food and Drug Administration 2015
Materias:
Special Invited Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351780/
https://www.ncbi.nlm.nih.gov/pubmed/28911371
http://dx.doi.org/10.1016/j.jfda.2015.03.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351780/
https://www.ncbi.nlm.nih.gov/pubmed/28911371
http://dx.doi.org/10.1016/j.jfda.2015.03.001

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