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LTβR overexpression promotes plasma cell accumulation

Multiple myeloma (MM), a malignancy of plasma cells (PCs), has diverse genetic underpinnings and in rare cases these include amplification of the lymphotoxin b receptor (Ltbr) locus. LTβR has well defined roles in supporting lymphoid tissue development and function through actions in stromal and mye...

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Detalles Bibliográficos
Autores principales: Kotov, Jessica A., Xu, Ying, Carey, Nicholas D., Cyster, Jason G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352096/
https://www.ncbi.nlm.nih.gov/pubmed/35925983
http://dx.doi.org/10.1371/journal.pone.0270907