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LTβR overexpression promotes plasma cell accumulation
Multiple myeloma (MM), a malignancy of plasma cells (PCs), has diverse genetic underpinnings and in rare cases these include amplification of the lymphotoxin b receptor (Ltbr) locus. LTβR has well defined roles in supporting lymphoid tissue development and function through actions in stromal and mye...
Autores principales: | Kotov, Jessica A., Xu, Ying, Carey, Nicholas D., Cyster, Jason G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352096/ https://www.ncbi.nlm.nih.gov/pubmed/35925983 http://dx.doi.org/10.1371/journal.pone.0270907 |
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