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Serotonin 1A Receptor Binding of [(11)C]CUMI-101 in Bipolar Depression Quantified Using Positron Emission Tomography: Relationship to Psychopathology and Antidepressant Response

BACKGROUND: The pathophysiology of bipolar disorder (BD) remains largely unknown despite it causing significant disability and suicide risk. Serotonin signaling may play a role in the pathophysiology, but direct evidence for this is lacking. Treatment of the depressed phase of the disorder is limite...

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Detalles Bibliográficos
Autores principales: Lan, Martin J, Zanderigo, Francesca, Pantazatos, Spiro P, Sublette, M Elizabeth, Miller, Jeffrey, Ogden, R Todd, Mann, J John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352178/
https://www.ncbi.nlm.nih.gov/pubmed/34996114
http://dx.doi.org/10.1093/ijnp/pyac001