Cargando…

Omicron BA.1 and BA.2 variants increase the interactions of SARS-CoV-2 spike glycoprotein with ACE2

SARS-CoV-2 infection is initiated by binding of the receptor-binding domain (RBD) of its spike glycoprotein to the peptidase domain (PD) of angiotensin-converting enzyme 2 (ACE2) receptors in host cells. Recently detected Omicron variant of SARS-CoV-2 (B.1.1.529) is heavily mutated on RBD. First the...

Descripción completa

Detalles Bibliográficos
Autores principales: Golcuk, Mert, Yildiz, Ahmet, Gur, Mert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352197/
https://www.ncbi.nlm.nih.gov/pubmed/35964366
http://dx.doi.org/10.1016/j.jmgm.2022.108286