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Impaired astrocytic Ca(2+) signaling in awake-behaving Alzheimer’s disease transgenic mice

Increased astrocytic Ca(2+) signaling has been shown in Alzheimer’s disease mouse models, but to date no reports have characterized behaviorally induced astrocytic Ca(2+) signaling in such mice. Here, we employ an event-based algorithm to assess astrocytic Ca(2+) signals in the neocortex of awake-be...

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Detalles Bibliográficos
Autores principales: Åbjørsbråten, Knut Sindre, Skaaraas, Gry HE Syverstad, Cunen, Céline, Bjørnstad, Daniel M, Binder, Kristin M Gullestad, Bojarskaite, Laura, Jensen, Vidar, Nilsson, Lars NG, Rao, Shreyas B, Tang, Wannan, Hermansen, Gudmund Horn, Nagelhus, Erlend A, Ottersen, Ole Petter, Torp, Reidun, Enger, Rune
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352348/
https://www.ncbi.nlm.nih.gov/pubmed/35833623
http://dx.doi.org/10.7554/eLife.75055