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A combined metabolomics and molecular biology approach to reveal hepatic injury and underlying mechanisms after chronic l-lactate exposure in mice

This study aimed to explore whether chronic l-lactate exposure could affect the peripheral tissues of mice and to determine the underlying pathogenesis. Herein, male C57BL/6 mice were divided into control and l-lactate groups. After l-lactate treatment for eight weeks (1 g/kg), metabolic changes in...

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Detalles Bibliográficos
Autores principales: Dong, Minjian, Yi, Qingqing, Shen, Danjie, Yan, Jiapin, Jiang, Haowei, Xie, Jiaojiao, Zhao, Liangcai, Gao, Hongchang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352416/
https://www.ncbi.nlm.nih.gov/pubmed/35950184
http://dx.doi.org/10.1016/j.csbj.2022.07.034