Intratumoral IL-28B Gene Delivery Elicits Antitumor Effects by Remodeling of the Tumor Microenvironment in H22-Bearing Mice

IL-28B, belonging to type III interferons (IFN-λs), exhibits a potent antitumor activity with reduced regulated T cells (Tregs) population, yet the effect of IL-28B on the tumor microenvironment (TME) and if IL-28B can downregulate Tregs directly in vitro are still unknown. In this study, we investi...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Zhi, Wang, Jianghua, Chen, Chong, He, Qi, Xu, Xiaoying, Da, Zejiao, Wang, Bo, Wang, Meng, Gao, Xiaotong, Zhang, Guochao, Gao, Qi, Si, Xiaoli, Luo, Yanping, Ma, Xingming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352479/
https://www.ncbi.nlm.nih.gov/pubmed/35935577
http://dx.doi.org/10.1155/2022/1345971

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352479/
https://www.ncbi.nlm.nih.gov/pubmed/35935577
http://dx.doi.org/10.1155/2022/1345971

Ejemplares similares