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Energetic determinants of animal cell polarity regulator Par-3 interaction with the Par complex

The animal cell polarity regulator Par-3 recruits the Par complex (consisting of Par-6 and atypical PKC, aPKC) to specific sites on the cell membrane. Although numerous physical interactions have been reported between Par-3 and the Par complex, it is unclear how each of these interactions contribute...

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Detalles Bibliográficos
Autores principales: Penkert, Rhiannon R., Vargas, Elizabeth, Prehoda, Kenneth E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352551/
https://www.ncbi.nlm.nih.gov/pubmed/35787373
http://dx.doi.org/10.1016/j.jbc.2022.102223