Stage-specific transcription activator ESB1 regulates monoallelic antigen expression in Trypanosoma brucei

Variant surface glycoprotein (VSG) coats bloodstream form Trypanosoma brucei parasites, and monoallelic VSG expression underpins the antigenic variation necessary for pathogenicity. One of thousands of VSG genes is transcribed by RNA polymerase I in a singular nuclear structure called the expression...

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Detalles Bibliográficos
Autores principales: López-Escobar, Lara, Hänisch, Benjamin, Halliday, Clare, Ishii, Midori, Akiyoshi, Bungo, Dean, Samuel, Sunter, Jack Daniel, Wheeler, Richard John, Gull, Keith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352583/
https://www.ncbi.nlm.nih.gov/pubmed/35879525
http://dx.doi.org/10.1038/s41564-022-01175-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352583/
https://www.ncbi.nlm.nih.gov/pubmed/35879525
http://dx.doi.org/10.1038/s41564-022-01175-z

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