Relationships between genome-wide R-loop distribution and classes of recurrent DNA breaks in neural stem/progenitor cells

Recent studies revealed classes of recurrent DNA double-strand breaks (DSBs) in neural stem/progenitor cells, including transcription-associated, promoter-proximal breaks and recurrent DSB clusters in late-replicating, long neural genes that may give rise to somatic brain mosaicism. The mechanistic...

Descripción completa

Detalles Bibliográficos
Autores principales: Thongthip, Supawat, Carlson, Annika, Crossley, Magdalena P., Schwer, Bjoern
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352722/
https://www.ncbi.nlm.nih.gov/pubmed/35927309
http://dx.doi.org/10.1038/s41598-022-17452-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352722/
https://www.ncbi.nlm.nih.gov/pubmed/35927309
http://dx.doi.org/10.1038/s41598-022-17452-0

Ejemplares similares