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Nuclear β-catenin translocation plays a key role in osteoblast differentiation of giant cell tumor of bone

Denosumab is a game-changing drug for giant cell tumor of bone (GCTB); however, its clinical biomarker regarding tumor ossification of GCTB has not been elucidated. In this study, we investigated the relationship between Wnt/β-catenin signaling and the ossification of GCTB and evaluated whether endo...

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Detalles Bibliográficos
Autores principales: Kimura, Atsushi, Toda, Yu, Matsumoto, Yoshihiro, Yamamoto, Hidetaka, Yahiro, Kenichiro, Shimada, Eijiro, Kanahori, Masaya, Oyama, Ryunosuke, Fukushima, Suguru, Nakagawa, Makoto, Setsu, Nokitaka, Endo, Makoto, Fujiwara, Toshifumi, Matsunobu, Tomoya, Oda, Yoshinao, Nakashima, Yasuharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352730/
https://www.ncbi.nlm.nih.gov/pubmed/35927428
http://dx.doi.org/10.1038/s41598-022-17728-5