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Nuclear β-catenin translocation plays a key role in osteoblast differentiation of giant cell tumor of bone
Denosumab is a game-changing drug for giant cell tumor of bone (GCTB); however, its clinical biomarker regarding tumor ossification of GCTB has not been elucidated. In this study, we investigated the relationship between Wnt/β-catenin signaling and the ossification of GCTB and evaluated whether endo...
Autores principales: | Kimura, Atsushi, Toda, Yu, Matsumoto, Yoshihiro, Yamamoto, Hidetaka, Yahiro, Kenichiro, Shimada, Eijiro, Kanahori, Masaya, Oyama, Ryunosuke, Fukushima, Suguru, Nakagawa, Makoto, Setsu, Nokitaka, Endo, Makoto, Fujiwara, Toshifumi, Matsunobu, Tomoya, Oda, Yoshinao, Nakashima, Yasuharu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352730/ https://www.ncbi.nlm.nih.gov/pubmed/35927428 http://dx.doi.org/10.1038/s41598-022-17728-5 |
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