TNF-α promotes α-synuclein propagation through stimulation of senescence-associated lysosomal exocytosis

Cell-to-cell propagation of α-synuclein is thought to be the underlying mechanism of Parkinson’s disease progression. Recent evidence suggests that inflammation plays an important role in the propagation of protein aggregates. However, the mechanism by which inflammation regulates the propagation of...

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Detalles Bibliográficos
Autores principales: Bae, Eun-Jin, Choi, Minsun, Kim, Jeong Tae, Kim, Dong-Kyu, Jung, Min Kyo, Kim, Changyoun, Kim, Tae-Kyung, Lee, Jun Sung, Jung, Byung Chul, Shin, Soo Jean, Rhee, Ka Hyun, Lee, Seung-Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352737/
https://www.ncbi.nlm.nih.gov/pubmed/35790884
http://dx.doi.org/10.1038/s12276-022-00789-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352737/
https://www.ncbi.nlm.nih.gov/pubmed/35790884
http://dx.doi.org/10.1038/s12276-022-00789-x

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