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TNF-α promotes α-synuclein propagation through stimulation of senescence-associated lysosomal exocytosis
Cell-to-cell propagation of α-synuclein is thought to be the underlying mechanism of Parkinson’s disease progression. Recent evidence suggests that inflammation plays an important role in the propagation of protein aggregates. However, the mechanism by which inflammation regulates the propagation of...
Autores principales: | Bae, Eun-Jin, Choi, Minsun, Kim, Jeong Tae, Kim, Dong-Kyu, Jung, Min Kyo, Kim, Changyoun, Kim, Tae-Kyung, Lee, Jun Sung, Jung, Byung Chul, Shin, Soo Jean, Rhee, Ka Hyun, Lee, Seung-Jae |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352737/ https://www.ncbi.nlm.nih.gov/pubmed/35790884 http://dx.doi.org/10.1038/s12276-022-00789-x |
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