Synaptotagmin-13 orchestrates pancreatic endocrine cell egression and islet morphogenesis

During pancreas development endocrine cells leave the ductal epithelium to form the islets of Langerhans, but the morphogenetic mechanisms are incompletely understood. Here, we identify the Ca(2+)-independent atypical Synaptotagmin-13 (Syt13) as a key regulator of endocrine cell egression and islet...

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Detalles Bibliográficos
Autores principales: Bakhti, Mostafa, Bastidas-Ponce, Aimée, Tritschler, Sophie, Czarnecki, Oliver, Tarquis-Medina, Marta, Nedvedova, Eva, Jaki, Jessica, Willmann, Stefanie J., Scheibner, Katharina, Cota, Perla, Salinno, Ciro, Boldt, Karsten, Horn, Nicola, Ueffing, Marius, Burtscher, Ingo, Theis, Fabian J., Coskun, Ünal, Lickert, Heiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352765/
https://www.ncbi.nlm.nih.gov/pubmed/35927244
http://dx.doi.org/10.1038/s41467-022-31862-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352765/
https://www.ncbi.nlm.nih.gov/pubmed/35927244
http://dx.doi.org/10.1038/s41467-022-31862-8

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