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Neutrophil extracellular traps are involved in enhanced contact hypersensitivity response in IL-36 receptor antagonist-deficient mice

Loss-of-function homozygous or compound heterozygous mutations in IL36RN, which encodes interleukin-36 receptor antagonist (IL-36Ra), have been implicated in the pathogenesis of skin disorders. We previously reported that Il36rn(−/−) mice exhibit an enhanced contact hypersensitivity (CHS) response t...

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Detalles Bibliográficos
Autores principales: Hasegawa, Yurie, Iwata, Yohei, Fukushima, Hidehiko, Tanaka, Yoshihito, Watanabe, Soichiro, Saito, Kenta, Ito, Hiroyuki, Sugiura, Mizuki, Akiyama, Masashi, Sugiura, Kazumitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352770/
https://www.ncbi.nlm.nih.gov/pubmed/35927298
http://dx.doi.org/10.1038/s41598-022-16449-z