AAV-mediated delivery of osteoblast/osteoclast-regulating miRNAs for osteoporosis therapy

Osteoporosis occurs due to a dysregulation in bone remodeling, a process requiring both bone-forming osteoblasts and bone-resorbing osteoclasts. Current leading osteoporosis therapies suppress osteoclast-mediated bone resorption but show limited therapeutic effects because osteoblast-mediated bone f...

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Detalles Bibliográficos
Autores principales: John, Aijaz Ahmad, Xie, Jun, Yang, Yeon-Suk, Kim, Jung-Min, Lin, Chujiao, Ma, Hong, Gao, Guangping, Shim, Jae-Hyuck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352805/
https://www.ncbi.nlm.nih.gov/pubmed/35950212
http://dx.doi.org/10.1016/j.omtn.2022.07.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352805/
https://www.ncbi.nlm.nih.gov/pubmed/35950212
http://dx.doi.org/10.1016/j.omtn.2022.07.008

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