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Analysis of the OX40/OX40L immunoregulatory axis combined with alternative immune checkpoint molecules in pancreatic ductal adenocarcinoma

Immune checkpoint modulation has been a vital therapeutic option in many malignancies, and targeting of novel immune checkpoints, including OX40/OX40L costimulatory signaling, is being assessed in clinical trials. However, little is known about the role of OX40 and OX40L in pancreatic ductal adenoca...

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Detalles Bibliográficos
Autores principales: Chen, Xianlong, Ma, Heng, Mo, Shengwei, Zhang, Yue, Lu, Zhaohui, Yu, Shuangni, Chen, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352865/
https://www.ncbi.nlm.nih.gov/pubmed/35936015
http://dx.doi.org/10.3389/fimmu.2022.942154