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NXN suppresses metastasis of hepatocellular carcinoma by promoting degradation of Snail through binding to DUB3

The poor prognosis of hepatocellular carcinoma (HCC) could be attributed to its high metastasis rate. Here, we report the role of nucleoredoxin (NXN), a multifunctional redox-active protein, in HCC metastasis. The expression of NXN in HCC tissues was measured by immunohistochemistry. The role of NXN...

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Detalles Bibliográficos
Autores principales: Zhang, Yuanping, Zuo, Dinglan, Qiu, Jiliang, Li, Kai, Niu, Yi, Yuan, Yichuan, Qiu, Yuxiong, Qiao, Liang, He, Wei, Wang, Chenwei, Yuan, Yunfei, Li, Binkui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352874/
https://www.ncbi.nlm.nih.gov/pubmed/35927236
http://dx.doi.org/10.1038/s41419-022-05135-7