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Selenoprotein TXNRD3 supports male fertility via the redox regulation of spermatogenesis

Thioredoxin/glutathione reductase (TXNRD3) is a selenoprotein composed of thioredoxin reductase and glutaredoxin domains. This NADPH-dependent thiol oxidoreductase evolved through gene duplication within the Txnrd family, is expressed in the testes, and can reduce both thioredoxin and glutathione in...

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Detalles Bibliográficos
Autores principales: Dou, Qianhui, Turanov, Anton A., Mariotti, Marco, Hwang, Jae Yeon, Wang, Huafeng, Lee, Sang-Goo, Paulo, Joao A., Yim, Sun Hee, Gygi, Stephen P., Chung, Jean-Ju, Gladyshev, Vadim N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352919/
https://www.ncbi.nlm.nih.gov/pubmed/35753352
http://dx.doi.org/10.1016/j.jbc.2022.102183