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Selenoprotein TXNRD3 supports male fertility via the redox regulation of spermatogenesis
Thioredoxin/glutathione reductase (TXNRD3) is a selenoprotein composed of thioredoxin reductase and glutaredoxin domains. This NADPH-dependent thiol oxidoreductase evolved through gene duplication within the Txnrd family, is expressed in the testes, and can reduce both thioredoxin and glutathione in...
Autores principales: | Dou, Qianhui, Turanov, Anton A., Mariotti, Marco, Hwang, Jae Yeon, Wang, Huafeng, Lee, Sang-Goo, Paulo, Joao A., Yim, Sun Hee, Gygi, Stephen P., Chung, Jean-Ju, Gladyshev, Vadim N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352919/ https://www.ncbi.nlm.nih.gov/pubmed/35753352 http://dx.doi.org/10.1016/j.jbc.2022.102183 |
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