A probable cis-acting genetic modifier of Huntington disease frequent in individuals with African ancestry

Huntington disease (HD)is a dominantly inherited neurodegenerative disorder caused by the expansion of a polyglutamine encoding CAG repeat in the huntingtin gene. Recently, it has been established that disease severity in HD is best predicted by the number of pure CAG repeats rather than total gluta...

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Detalles Bibliográficos
Autores principales: Dawson, Jessica, Baine-Savanhu, Fiona K., Ciosi, Marc, Maxwell, Alastair, Monckton, Darren G., Krause, Amanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352962/
https://www.ncbi.nlm.nih.gov/pubmed/35935919
http://dx.doi.org/10.1016/j.xhgg.2022.100130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352962/
https://www.ncbi.nlm.nih.gov/pubmed/35935919
http://dx.doi.org/10.1016/j.xhgg.2022.100130

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