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Completing Single-Cell DNA Methylome Profiles via Transfer Learning Together With KL-Divergence

The high level of sparsity in methylome profiles obtained using whole-genome bisulfite sequencing in the case of low biological material amount limits its value in the study of systems in which large samples are difficult to assemble, such as mammalian preimplantation embryonic development. The rece...

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Detalles Bibliográficos
Autores principales: Dodlapati, Sanjeeva, Jiang, Zongliang, Sun, Jiangwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9353187/
https://www.ncbi.nlm.nih.gov/pubmed/35938031
http://dx.doi.org/10.3389/fgene.2022.910439