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Completing Single-Cell DNA Methylome Profiles via Transfer Learning Together With KL-Divergence
The high level of sparsity in methylome profiles obtained using whole-genome bisulfite sequencing in the case of low biological material amount limits its value in the study of systems in which large samples are difficult to assemble, such as mammalian preimplantation embryonic development. The rece...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9353187/ https://www.ncbi.nlm.nih.gov/pubmed/35938031 http://dx.doi.org/10.3389/fgene.2022.910439 |