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NPC1 Deficiency Contributes to Autophagy-Dependent Ferritinophagy in HEI-OC1 Auditory Cells

Niemann–Pick type C disease (NPCD) is a rare genetic syndrome characterized by cholesterol accumulation in multiple organelles. NPCD is mainly caused by gene deficiency of NPC intracellular cholesterol transporter 1 (NPC1). It has been reported that some of the NPCD patients exhibit clinical feature...

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Detalles Bibliográficos
Autores principales: Liang, Lihong, Wang, Hongshun, Yao, Jun, Wei, Qinjun, Lu, Yajie, Wang, Tianming, Cao, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9353266/
https://www.ncbi.nlm.nih.gov/pubmed/35936782
http://dx.doi.org/10.3389/fmolb.2022.952608