Cargando…

A Functional Screening Identifies a New Organic Selenium Compound Targeting Cancer Stem Cells: Role of c‐Myc Transcription Activity Inhibition in Liver Cancer

Cancer stem cells (CSCs) are reported to play essential roles in chemoresistance and metastasis. Pathways regulating CSC self‐renewal and proliferation, such as Hedgehog, Notch, Wnt/β‐catenin, TGF‐β, and Myc, may be potential therapeutic targets. Here, a functional screening from the focused library...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Jun‐Nian, Zhang, Biao, Wang, Hai‐Yang, Wang, Dong‐Xing, Zhang, Ming‐Ming, Zhang, Min, Wang, Xiao‐Kui, Fan, Shi‐Yong, Xu, Ying‐Chen, Zeng, Quan, Jia, Ya‐Li, Xi, Jia‐Fei, Nan, Xue, He, Li‐Juan, Zhou, Xin‐Bo, Li, Song, Zhong, Wu, Yue, Wen, Pei, Xue‐Tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9353477/ https://www.ncbi.nlm.nih.gov/pubmed/35652264 http://dx.doi.org/10.1002/advs.202201166

Ejemplares similares

Arsenic trioxide inhibits liver cancer stem cells and metastasis by targeting SRF/MCM7 complex
por: Wang, Hai-Yang, et al.
Publicado: (2019)

A new protocol for long‐term culture of a specific subpopulation of liver cancer stem cells enriched by cell surface markers
por: Zhang, Biao, et al.
Publicado: (2020)

Therapeutic Potential of Selenium and Selenium Compounds in Cervical Cancer
por: Jablonska, Ewa, et al.
Publicado: (2021)

Different Effects and Mechanisms of Selenium Compounds in Improving Pathology in Alzheimer’s Disease
por: Zhang, Zhong-Hao, et al.
Publicado: (2023)

PKM2–c-Myc–Survivin Cascade Regulates the Cell Proliferation, Migration, and Tamoxifen Resistance in Breast Cancer
por: Yu, Pian, et al.
Publicado: (2020)

MYC status as a determinant of synergistic response to Olaparib and Palbociclib in ovarian cancer
por: Yi, Jingyan, et al.
Publicado: (2019)

Cordycepin inhibits colon cancer proliferation by suppressing MYC expression
por: Zhang, Zhe, et al.
Publicado: (2022)

THAP11 Functions as a Tumor Suppressor in Gastric Cancer through Regulating c-Myc Signaling Pathways
por: Zhang, Jing, et al.
Publicado: (2020)

The Effects of Selenium on Wheat Fusarium Head Blight and DON Accumulation Were Selenium Compound-Dependent
por: Mao, Xueyun, et al.
Publicado: (2020)

SPAG5 upregulation contributes to enhanced c-MYC transcriptional activity via interaction with c-MYC binding protein in triple-negative breast cancer
por: Li, Ming, et al.
Publicado: (2019)

Cardiac function evaluation for a novel one-step detoxification product of Aconiti Lateralis Radix Praeparata
por: He, Ya-nan, et al.
Publicado: (2018)

Anti-silencing function 1B promotes the progression of pancreatic cancer by activating c-Myc
por: Zhang, Min, et al.
Publicado: (2022)

S-Adenosylmethionine Inhibits the Growth of Cancer Cells by Reversing the Hypomethylation Status of c-myc and H-ras in Human Gastric Cancer and Colon Cancer
por: Luo, Jin, et al.
Publicado: (2010)

ANXA2 promotes esophageal cancer progression by activating MYC-HIF1A-VEGF axis
por: Ma, Sai, et al.
Publicado: (2018)

Selenophosphate synthetase 1 (SPS1) is required for the development and selenium homeostasis of central nervous system in chicken (Gallus gallus)
por: Li, Jin-Long, et al.
Publicado: (2017)

Rs10757274 gene polymorphisms in coronary artery disease: A systematic review and a meta-analysis
por: Xu, Lang-Biao, et al.
Publicado: (2020)

PTPN18 promotes colorectal cancer progression by regulating the c-MYC-CDK4 axis
por: Li, Chao, et al.
Publicado: (2020)

Targeting the cholesterol-RORα/γ axis inhibits colorectal cancer progression through degrading c-myc
por: Wang, Ying-Nan, et al.
Publicado: (2022)

The Evi5 oncogene promotes laryngeal cancer cells proliferation by stabilizing c-Myc protein
por: Mao, Cheng-Gang, et al.
Publicado: (2020)

Assessing Plasma Levels of Selenium, Copper, Iron and Zinc in Patients of Parkinson’s Disease
por: Zhao, Hai-Wen, et al.
Publicado: (2013)

Microfluidic Analysis for Separating and Measuring the Deformability of Cancer Cell Subpopulations
por: Chang, Ya-Nan, et al.
Publicado: (2019)

Neurokinin-1 receptor drives PKCɑ-AURKA/N-Myc signaling to facilitate the neuroendocrine progression of prostate cancer
por: Zhang, Xiao-Wei, et al.
Publicado: (2023)

Generation and Immunity Testing of a Recombinant Adenovirus Expressing NcSRS2-NcGRA7 Fusion Protein of Bovine Neospora caninum
por: Jia, Li-Jun, et al.
Publicado: (2013)

Screening of the Active Compounds against Neural Oxidative Damage from Ginseng Phloem Using UPLC-Q-Exactive-MS/MS Coupled with the Content-Effect Weighted Method
por: Gao, Xiao-Chen, et al.
Publicado: (2022)

Transcriptomic Insights into the Response of the Olfactory Bulb to Selenium Treatment in a Mouse Model of Alzheimer’s Disease
por: Zheng, Rui, et al.
Publicado: (2019)

Comparison of HER2 status by fluorescence in situ hybridisation and immunohistochemistry in gastric cancer
por: Chen, Ming, et al.
Publicado: (2014)

C-myc/TSPEAR-AS2 Axis Facilitates Breast Cancer Growth and Metastasis in a GLUT1-Dependent Glycolysis Manner
por: Xu, Jian, et al.
Publicado: (2022)

MYC overexpression with its prognostic and clinicopathological significance in breast cancer
por: Qu, Jingkun, et al.
Publicado: (2017)

Computational study on natural compounds inhibitor of c-Myc
por: Ren, Junan, et al.
Publicado: (2020)

PKCδ promotes the invasion and migration of colorectal cancer through c-myc/NDRG1 pathway
por: Jia, Hong-tao, et al.
Publicado: (2023)

Jumonji domain-containing protein 1A promotes cell growth and progression via transactivation of c-Myc expression and predicts a poor prognosis in cervical cancer
por: Liu, Jue, et al.
Publicado: (2016)

Pan-Cancer Study of the Prognosistic Value of Selenium Phosphate Synthase 1
por: Hao, Jie, et al.
Publicado: (2023)

The Association of Circulating Selenium Concentrations with Diabetes Mellitus
por: Liao, Xiao-Long, et al.
Publicado: (2020)

Selenium Species: Current Status and Potentials in Cancer Prevention and Therapy
por: Tan, Heng Wee, et al.
Publicado: (2018)

Diclofenac impairs the proliferation and glucose metabolism of triple-negative breast cancer cells by targeting the c-Myc pathway
por: Yang, Lihui, et al.
Publicado: (2021)

METTL3 Promotes the Progression of Gastric Cancer via Targeting the MYC Pathway
por: Yang, Dong-Dong, et al.
Publicado: (2020)

Long non-coding RNA HOTAIR, a c-Myc activated driver of malignancy, negatively regulates miRNA-130a in gallbladder cancer
por: Ma, Ming-zhe, et al.
Publicado: (2014)

An ingenious method for the determination of the relative and absolute configurations of compounds containing aryl-glycerol fragments by (1)H NMR spectroscopy
por: Zhang, Xu, et al.
Publicado: (2021)

MYC Regulates PHF8, Which Promotes the Progression of Gastric Cancer by Suppressing miR-22-3p
por: Cai, Ming-Zhi, et al.
Publicado: (2020)

Enzyme-catalyzed synthesis of selenium-doped manganese phosphate for synergistic therapy of drug-resistant colorectal cancer
por: Pei, Manman, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_s3fe42m92f73g7v8nvsed3hcso