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A Novel Berberine–Glycyrrhizic Acid Complex Formulation Enhanced the Prevention Effect to Doxorubicin-Induced Cardiotoxicity by Pharmacokinetic Modulation of Berberine in Rats

Developing a new drug delivery system is one of the useful approaches to overcome the limited use of berberine (BBR) to enhance its absorption and bioavailability. We prepared a novel berberine–glycyrrhizic acid (BBR–GL) complex formulation to increase the plasma concentration and bioavailability of...

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Detalles Bibliográficos
Autores principales: Zhang, Shichang, Zhao, Yiwei, Tan, Liangjun, Wu, Sheng, Zhang, Qing, Zhao, Boxin, Li, Guofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9353711/
https://www.ncbi.nlm.nih.gov/pubmed/35935857
http://dx.doi.org/10.3389/fphar.2022.891829