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In silico integrative analysis of multi-omics reveals regulatory layers for diurnal gene expression in mouse liver

Diurnal oscillation persists throughout the body and plays an essential role in maintaining physiological homeostasis. Disruption of diurnal rhythm contributes to many diseases including type 2 diabetes. The regulatory mechanism of the transcription-translation feedback loop (TTFL) of core clock gen...

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Detalles Bibliográficos
Autores principales: Jiang, Chunjie, Liu, Panpan, La, Cam Mong, Guan, Dongyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9353712/
https://www.ncbi.nlm.nih.gov/pubmed/35937828
http://dx.doi.org/10.3389/fendo.2022.955070