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Advances and challenges of CAR T therapy and suitability of animal models (Review)

Chimeric antigen receptors (CARs) recently gained momentum in cancer treatment due to their ability to promote T-cell mediated responses to a specific tumor-associated antigen. CARs are part of the adoptive cell transfer (ACT) strategies that utilize patients' T lymphocytes, genetically enginee...

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Detalles Bibliográficos
Autores principales: Ramos-Cardona, Xavier E., Luo, Weichuan, Mohammed, Sulma I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9353808/
https://www.ncbi.nlm.nih.gov/pubmed/35949897
http://dx.doi.org/10.3892/mco.2022.2567