Metabonomic analysis of abnormal sphingolipid metabolism in rheumatoid arthritis synovial fibroblasts in hypoxia microenvironment and intervention of geniposide

Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by a joint hypoxia microenvironment. Our previous untargeted metabolomics study found that sphingolipid (SPL) metabolism was abnormal in the joint synovial fluid samples from adjuvant arthritis (AA) rats. Geniposide (GE), an i...

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Detalles Bibliográficos
Autores principales: Ke, Jiang-Tao, Zhang, Heng, Bu, Yan-Hong, Gan, Pei-Rong, Chen, Fang-Yuan, Dong, Xin-Tong, Wang, Yan, Wu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9353937/
https://www.ncbi.nlm.nih.gov/pubmed/35935818
http://dx.doi.org/10.3389/fphar.2022.969408

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9353937/
https://www.ncbi.nlm.nih.gov/pubmed/35935818
http://dx.doi.org/10.3389/fphar.2022.969408

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