Age-related increase of mitochondrial content in human memory CD4+ T cells contributes to ROS-mediated increased expression of proinflammatory cytokines

Cellular metabolism modulates effector functions in human CD4(+) T (Th) cells by providing energy and building blocks. Conversely, cellular metabolic responses are modulated by various influences, e.g., age. Thus, we hypothesized that metabolic reprogramming in human Th cells during aging modulates...

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Detalles Bibliográficos
Autores principales: Chen, Yuling, Ye, Yuanchun, Krauß, Pierre-Louis, Löwe, Pelle, Pfeiffenberger, Moritz, Damerau, Alexandra, Ehlers, Lisa, Buttgereit, Thomas, Hoff, Paula, Buttgereit, Frank, Gaber, Timo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9353942/
https://www.ncbi.nlm.nih.gov/pubmed/35935995
http://dx.doi.org/10.3389/fimmu.2022.911050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9353942/
https://www.ncbi.nlm.nih.gov/pubmed/35935995
http://dx.doi.org/10.3389/fimmu.2022.911050

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