TIE-2 Signaling Activation by Angiopoietin 2 On Myeloid-Derived Suppressor Cells Promotes Melanoma-Specific T-cell Inhibition

Myeloid-derived suppressor cells (MDSCs) are a heterogeneous group of immune suppressive cells detected in several human cancers. In this study, we investigated the features and immune suppressive function of a novel subset of monocytic MDSC overexpressing TIE-2 (TIE-2(+) M-MDSC), the receptor for t...

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Detalles Bibliográficos
Autores principales: Marguier, Amélie, Laheurte, Caroline, Lecoester, Benoît, Malfroy, Marine, Boullerot, Laura, Renaudin, Adeline, Seffar, Evan, Kumar, Abhishek, Nardin, Charlée, Aubin, François, Adotevi, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9353943/
https://www.ncbi.nlm.nih.gov/pubmed/35935946
http://dx.doi.org/10.3389/fimmu.2022.932298

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9353943/
https://www.ncbi.nlm.nih.gov/pubmed/35935946
http://dx.doi.org/10.3389/fimmu.2022.932298

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