Cargando…
Mitigating cold-start problems in drug-target affinity prediction with interaction knowledge transferring
Predicting the drug-target interaction is crucial for drug discovery as well as drug repurposing. Machine learning is commonly used in drug-target affinity (DTA) problem. However, the machine learning model faces the cold-start problem where the model performance drops when predicting the interactio...
Autores principales: | Nguyen, Tri Minh, Nguyen, Thin, Tran, Truyen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9353967/ https://www.ncbi.nlm.nih.gov/pubmed/35788823 http://dx.doi.org/10.1093/bib/bbac269 |
Ejemplares similares
-
Assessing polygenic risk score models for applications in populations with under-represented genomics data: an example of Vietnam
por: Pham, Duy, et al.
Publicado: (2022) -
Consensus clustering of single-cell RNA-seq data by enhancing network affinity
por: Cui, Yaxuan, et al.
Publicado: (2021) -
e-TSN: an interactive visual exploration platform for target–disease knowledge mapping from literature
por: Feng, Ziyan, et al.
Publicado: (2022) -
EXPERT: transfer learning-enabled context-aware microbial community classification
por: Chong, Hui, et al.
Publicado: (2022) -
HGTphyloDetect: facilitating the identification and phylogenetic analysis of horizontal gene transfer
por: Yuan, Le, et al.
Publicado: (2023)