AXL Promotes Metformin-Induced Apoptosis Through Mediation of Autophagy by Activating ROS-AMPK-ULK1 Signaling in Human Esophageal Adenocarcinoma

AXL receptor tyrosine kinase promotes an invasive phenotype and chemotherapy resistance in esophageal adenocarcinoma (EAC). AXL has been implicated in the regulation of autophagy, but the underlying molecular mechanism remains poorly understood. Herein, we investigate the mechanistic role of AXL in...

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Detalles Bibliográficos
Autores principales: Hong, Jun, Maacha, Selma, Pidkovka, Nataliya, Bates, Andreia, Salaria, Safia N., Washington, Mary K., Belkhiri, Abbes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354051/
https://www.ncbi.nlm.nih.gov/pubmed/35936716
http://dx.doi.org/10.3389/fonc.2022.903874

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354051/
https://www.ncbi.nlm.nih.gov/pubmed/35936716
http://dx.doi.org/10.3389/fonc.2022.903874

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