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Single-cell transcriptomics of staged oocytes and somatic cells reveal novel regulators of follicle activation

IN BRIEF: Proper development of ovarian follicles, comprised of an oocyte and surrounding somatic cells, is essential to support female fertility and endocrine health. Here, we describe a method to isolate single oocytes and somatic cells from the earliest stage follicles, called primordial follicle...

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Detalles Bibliográficos
Autores principales: Chen, Yu-Ying, Russo, Daniela D, Drake, Riley S, Duncan, Francesca E, Shalek, Alex K, Goods, Brittany A, Woodruff, Teresa K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354060/
https://www.ncbi.nlm.nih.gov/pubmed/35899878
http://dx.doi.org/10.1530/REP-22-0053