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Differential vulnerability of locus coeruleus and dorsal raphe neurons to chronic methamphetamine-induced degeneration

Methamphetamine (meth) increases monoamine oxidase (MAO)-dependent mitochondrial stress in axons of substantia nigra pars compacta (SNc), and ventral tegmental area (VTA) dopamine neurons. Chronic administration of meth results in SNc degeneration and MAO inhibition is neuroprotective, whereas, the...

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Detalles Bibliográficos
Autores principales: Du, Yijuan, Choi, Sanghoon, Pilski, Alexander, Graves, Steven M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354074/
https://www.ncbi.nlm.nih.gov/pubmed/35936499
http://dx.doi.org/10.3389/fncel.2022.949923