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Synthesis and Application of a Clickable Epoxomicin‐Based Probe for Proteasome Activity Analysis
The proteasome is a multisubunit protein complex responsible for the degradation of proteins, making it essential in myriad cellular processes. Several reversible and irreversible peptide substrates inspired by known proteasome inhibitors have been developed to visualize it and monitor its activity;...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354099/ https://www.ncbi.nlm.nih.gov/pubmed/35849029 http://dx.doi.org/10.1002/cpz1.490 |